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KMID : 0829320130160040162
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Korean Journal of Clinical Microbiology
2013 Volume.16 No. 4 p.162 ~ p.167
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The Human Microbiome Project: Beginning and Future Status
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Murray Patrick R.
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Abstract
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In 1884 Robert Koch and Friedrich Loeffler published Koch’s Postulates defining our historical understanding of the relationship between an organism and infection: one organism: one disease. In the last decade with research on the microbial community living on and in humans, a new concept of microbial diseases has emerged; that is, alterations of the microbial community can lead to disease including an extension beyond traditional “infectious” diseases to include metabolic disorders such as type 2 diabetes and obesity. As we continue to gain knowledge about the functions of the normal microbiome and the effects of alterations of the microbial population on disease pathogenesis, a new era of diagnostics and therapeutics will evolve.
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KEYWORD
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